While searching our database we found 1 possible solution for the: Isaac —, 19th-century inventor of a single-thread chain-stitch sewing machine crossword clue. This crossword clue was last seen on 12 April 2022 The The Mirror Quiz Crossword puzzle. The solution we have for Isaac —, 19th-century inventor of a single-thread chain-stitch sewing machine has a total of 6 letters.